sedative
New member
- Joined
- Jun 29, 2026
- Posts
- 5
- Reaction score
- 12
what is erdafitinib?
yeye we all know erda opens growth zones rite, its a cancer drug which inhibits fgfr1-4. fgfr3 acts as a brake on the growth plates, hence blocking it will increase growth plate activity
what are FGFRs?
Fibroblast Growth Factor Receptors are a family of receptor tyrosine kinases (fgfr1-fgfr4) that receive signals telling cells when to grow, divide, and survive, leading to the development of various types of cancers
ye fgfr3 is a growth limiter, so does inhibiting fgfr3 with erda increase growth?
lets look at some studies..
study 1
tldr: 2 children developed an increase in growth velocity after erda along with widening of growth plates
study 2
tldr: pre pubescent child grew 14.3 cm during treatment and developed skeletal deformities including scoliosis and kyphosis on erda
conclusion
erdafitinib can cause increase in growth velocity because it blocks FGFRs signaling, sometimes causing deformities as studies show effects only on children with open growth plates.. there are no results of erda increasing height on healthy people
so don’t be a retard, because there will be consequences if u dose it incorrectly or use without the proper ancillaries
yeye we all know erda opens growth zones rite, its a cancer drug which inhibits fgfr1-4. fgfr3 acts as a brake on the growth plates, hence blocking it will increase growth plate activity
what are FGFRs?
Fibroblast Growth Factor Receptors are a family of receptor tyrosine kinases (fgfr1-fgfr4) that receive signals telling cells when to grow, divide, and survive, leading to the development of various types of cancers
ye fgfr3 is a growth limiter, so does inhibiting fgfr3 with erda increase growth?
lets look at some studies..
study 1
tldr: 2 children developed an increase in growth velocity after erda along with widening of growth plates
study 2
tldr: pre pubescent child grew 14.3 cm during treatment and developed skeletal deformities including scoliosis and kyphosis on erda
conclusion
erdafitinib can cause increase in growth velocity because it blocks FGFRs signaling, sometimes causing deformities as studies show effects only on children with open growth plates.. there are no results of erda increasing height on healthy people
so don’t be a retard, because there will be consequences if u dose it incorrectly or use without the proper ancillaries